Introduction to Mathematical and Computational Systems Biology.

Catalog description

PR: MATH 261 with a minimum grade of C- and PR or CONC: ( MATH 343 or MATH 441 ) with a minimum grade of C-. Systems biology provides a framework to predict and control behaviors of large biochemical networks based on the analysis of its modules. Its methods apply to pharmacology, population dynamics, and epidemiology. Starting from concepts and computational implementation of biochemical kinetics, parameter fitting, sensitivity analysis, we develop principles for network control and analysis, with hands-on examples of metabolic, signaling, and genetic networks.