Drug Dosage Form Development Laboratory.

Catalog description

Semester course; 2 laboratory hours. 1 credit. Prerequisite: PSCZ 425 . Corequisite: PSCI 370 . Enrollment is restricted to students enrolled in the B.S. in Pharmaceutical Sciences or by permission of instructor. The laboratory course supports hands on experiential learning related to the design of dosage forms using a Quality-by-Design approach, and their characterization using United States Pharmacopeia compendial testing and Good Laboratory Practice, artificial intelligence in pharmaceutical dosage form development. A variety of traditional dosage forms will be explored, including oral tablets, injectables and nebulizers. Advanced drug delivery systems including lipid-based nanocarriers for small molecules and biologics including mRNA will also be explored. Analytical methods studied previously will be used in the course to characterize dosage forms, including assays for dose content uniformity, dissolution, purity, drug product stability, residual solvent, and drug loading and controlled release. Extensive characterization of the quality attributes of the formulations will be emphasized.