Drug Dosage Form Development.

Catalog description

Semester course; 2 lecture hours. 2 credits. Prerequisite: PSCI 420 . Corequisite: PSCZ 375 . Enrollment is restricted to students in the B.S. in Pharmaceutical Sciences program or by permission of the instructor. The course will introduce students to the basic principles and foundations of drug delivery and dosage form development, including solubility, kinetic processes, bioavailability, and excipient activities, basic colloidal and interfacial sciences concepts, as well as concepts in Quality-by-Design and artificial intelligence in pharmaceutical drug product development. Situations requiring innovative approaches to therapeutic treatment, such as design of pro-drugs for active pharmaceutical ingredients with low oral bioavailability and formulation of nanomedicines to improve drug stability, as in mRNA vaccines, will be discussed. Oral dosage forms such as capsules and tablets and non-oral drug delivery approaches, including orally inhaled products, injectables and others will be explored.