Cellular Mechanisms of Toxicology.

Catalog description

Semester course; 3 lecture hours. 3 credits. Prerequisite: PHTX 536 or permission of instructor. A holistic approach is taken to describe and analyze toxicological information. Intact animal, organ, cellular, and biochemical responses to toxic agents are presented. Immunologic, genetic, endocrine, and central nervous system paradigms and their relationship to the mechanism of action of toxic agents as well as the predictive value of tests of these systems are presented. Kinetics and metabolism of toxic agents as well as statistical and analytical procedures are integrated into the discussions.