Pharmaceutical Engineering Fundamentals I.

Catalog description

Semester course; 3 lecture hours (delivered online or face-to-face). 3 credits. Enrollment is restricted to pharmaceutical engineering graduate students or by permission of the instructor. An introductory course designed to expose students to basic concepts in drug discovery as well as principles in pharmaceutics, biopharmaceutics and pharmacokinetics that are fundamental to the development of various dosage forms. Topics to be covered include a general survey from drug discovery to clinical trials; omics-guided drug target identification and strategies for the design of new drugs; the physicochemical characteristics of drugs and excipients; formulation, manufacturing and packaging of pharmaceutical dosage forms; drug and dosage form stability and degradation; physicochemical mechanisms of drug absorption, distribution, metabolism and elimination; and mathematical models and physiological principles used to describe ADME. Prior basic knowledge in chemistry, calculus and statistics is required. The course content is delivered through lectures, group discussions, in-class calculations, homework and online tools.