Epigenetics. (3-0) 3 Credit Hours

Catalog description

Prerequisite: NDRB 3913 ; prior completion of BCH 2903 , BCH 3303 , or BCH 3313 is recommended. An exploration of heritable changes in gene expression that occur without alteration to the underlying DNA sequence. This course will introduce fundamental concepts of gene regulation by DNA methylation, histone modifications, chromatin remodeling, and non-coding RNA regulation. Specific topics will include the role of epigenetic regulation in development, chromosome inactivation, and chromatin dysfunction in cancer. Classical and emerging technologies used in chromatin biology and epigenetics will be covered. Generally offered: Spring. This course has Differential Tuition.