RNA Biology and Genomics I. 1 Credit Hour

Catalog description

This course, coupled with the course CSAT 5024 RNA Biology and Genomics II, covers the classical RNA functions as well as recent discoveries, such as RNA vaccines, RNA granules, and RNA modification, which were not covered by the previous RNA Biology and Genomics course. The RNA field is expanding due to several novel discoveries, such as RNA vaccines, RNA granules, and long-noncoding RNAs. To cover novel discoveries, this course focuses on the molecular mechanisms and physiological roles of post-transcriptional regulation of gene expressions, such as mRNA translation, RNA modifications, and RNA therapies, while CSAT 5024 covers splicing, non-coding RNA, and R-loops. The contents covered will be different between the CSAT 5024 and MMED 6001 . Another important component of these courses includes employing omics methods, such as RNA-seq, RIP-Seq, BRIC, CLIP, and Ribo-seq, to study these processes and regulators. Hands-on training on biological databases and classes covering examples of the use of genomics will be provided. We expect students to acquire skills that will help them visualize how genomics can be used in their own research projects.