RNA Biology and Genomics II. 1 Credit Hour

Catalog description

The challenges of controlling RNA viruses, the promise of RNA vaccines and the recent findings on the roles of ncRNAs and RNA binding proteins in human disease highlight the importance of studying RNA biology. This course, coupled with MMED 6001 , covers all aspects of RNA expression and metabolism, such as RNA processing, decay, transport, alternative splicing and translation and, the function of RNA binding proteins and non-coding RNAs. We will also discuss recent discoveries, such as RNA vaccines, RNA granules, RNA modification, the impact of RNA mediated processes in metabolic syndrome, neurodegenerative diseases and cancer and, RNA therapeutics. Another important goal of these courses is to teach students to employ omics methods such as RNA-seq, RIP-Seq, BRIC, CLIP, Ribo-seq, and CRISPR to study these processes and their regulators. This includes hands-on training on biological databases and classes covering examples of the use of genomics. We expect students to acquire skills that will help them visualize how RNA genomics can be used in their own research projects. Open for Cross Enrollment on Space Available Basis.