Advanced Developmental Biology

Catalog description

This course is intended for master's level students who understand genetics and cell biology/biochemistry. This course examines the molecular mechanisms of development covering fertilization through senescence. It is organized around an in depth analysis and careful reading of primary research papers taken from the current literature. Topics vary but include events in early embryogenesis such as fertilization, embryonic stem cells, gastrulation and layer determination, and axis formation. Later events in embryogenesis covered include tissue specific stem cells, digit formation, cell differentiation, muscle formation, neural development, and synapse formation. Postembryonic development includes studies on hormonal regulation, aging, and senescence. A variety of organisms are introduced, with common mechanisms of development emphasized. Prerequisite: An undergraduate degree in Biology or related discipline or permission from instructor.