Mechanisms of Disease.

Catalog description

This course provides an advanced, integrative examination of the molecular, cellular, and systems-level mechanisms underlying human disease, with an emphasis on genomic and precision medicine approaches.  Students will explore how genetic and epigenetic variation, dysregulated signaling pathways, and environmental factors contribute to disease initiation, progression, and heterogeneity across major disease categories, including cancer, metabolic disorders, immunological diseases, infectious diseases, cardiovascular disease, and aging.  A mechanistic and data-driven framework will be used to connect genomic variation to phenotype and clinical presentation.  (Fall Only).