Enzyme Kinetics and Mechanism

Catalog description

Pre-requisite: BCHM 8500. In this course the students will work with the concepts and applications of enzyme mechanisms with emphasis on the key kinetic and thermodynamic concepts that rule the activity of enzymes steady state kinetics, transient kinetics, mechanisms of catalysis, and mechanisms of inhibition. Methods to elucidate kinetic and chemical mechanisms will be explored such as kinetic isotope effect, spectroscopy and stopped- flow techniques. The students will have hands -on experience in the analysis of data by using softwa re for kinetics research.