Advanced Immunology: Signaling in the Immune System

Catalog description

The study of signaling pathways that regulate the immune response. BMB 432 / MICRB 432 / VBSC 432 Advanced Immunology: Signaling in the Immune System (3)This course will use the immune system as a model in which to study how cells communicate in order to coordinate an immune response. We will focus on signaling mechanisms that regulate such immune responses as T cell activation, Thl/Th2 differentiation, macrophage activation, and migration of immune cells to sites of inflammation. All lectures are based on recent reviews by key investigators in each field, as well as primary articles to present students with the most recent advances, techniques, and approaches used. The goal of the course will be to convey a basis understanding of intracellular signaling mechanisms that will pertain to all areas of biology, an appreciation for current questions and future directions in the field, and an in depth understanding of the signals that govern immune responses. The material presented will build on the basic concepts learned in BMB 400 and MICRB 410 , and will lay the foundation for more advanced courses at the graduate level.