Structural Analysis of Organic Compounds

Catalog description

Spectroscopic methods as tools in gross and detailed structural analysis and interpretation within the framework of modern theory. CHEM 430 CHEM 430 Structural Analysis of Organic Compounds (3) This course is designed to introduce students to the spectroscopic techniques that are used to elucidate the structures of organic molecules of various molecular weights. Some theoretical background will be provided and is necessary, but the emphasis is on solving problems. The course starts with fundamental concepts and techniques learned in sophomore organic chemistry and builds toward state-of-the-art methods used by modern organic and bioorganic chemists. Topics to be covered include: UV spectroscopy, 1D- 1H and 13C NMR, spin-spin (scalar) coupling and chemical shifts, IR spectroscopy, simple and advanced mass spectroscopic techniques, stereochemistry, advanced NMR topics including advanced 1D and2D NMR and correlation spectroscopies. Some consideration will also be given to the challenges associated with structure determination in biomolecules.