Organic Chemistry II

Catalog description

Continuation of CHEM 210 . Emphasis is placed on the role of organic reactions in biological chemistry. CHEM 212 CHEM 212 Organic Chemistry II (3) This course will continue to build upon the important concepts learned in the prerequisite course, CHEM 210 , with an emphasis on reactions mechanisms and organic synthesis. The course will begin with conceptually new material that will be applied in the laboratory course, namely, the elucidation of the structures of organic compounds using mass spectrometry, infrared spectroscopy and nuclear magnetic resonance spectroscopy. The majority of the new material is concerned with the chemistry of carbonyl compounds and includes: 1) the nucleophilic addition reactions of ketones and aldehydes; 2) nucleophilic acyl substitution reactions of acid chlorides, anhydrides, esters and amides; 3) carbonyl alpha-substitution reactions and 4) carbonyl condensation reactions. The latter part of the course will be concerned with biologically relevant compounds such as amines, amino acids/peptides/proteins and carbohydrates.