Regulation of Cellular & Systemic Energy Metabolism

Catalog description

Teaches biochemical and signal transduction concepts while exploring the control of bioenergetic processes. BMS 501 BMS 501 Regulations of Cellular & Systemic Energy Metabolism (3) Energy is fundamental to life. The production, storage and utilization of energy by organisms are highly regulated processes that provide excellent examples of the principals that govern the control of cellular metabolism and hormonal signaling. In addition, future biomedical scientists must be prepared to study diseases associated with aberrant energy metabolism, such as diabetes, obesity, and malnutrition. Regulation of Cellular & Systemic Energy Metabolism is one of three thematic courses that comprise the fall semester. The course explores how energy is obtained, stored and utilized by cells, tissues and organisms. The biochemistry of energy metabolism is studied with a focus on mechanisms by which these pathways are controlled in order to maintain health and energy homeostasis. Principles of hormonal signaling and cellular signal transduction pathways are studied in the context of energy metabolism. In addition, knowledge of these subjects is applied to the study of pathologies involving abnormal energy metabolism, including diabetes, obesity and starvation. Course objectives include developing an understanding of metabolic pathways and the mechanisms by which they are regulated; understanding principals of receptor theory, signal transduction and hormonal control of cellular processes; and gaining an understanding and appreciation of diseases that involve abnormal energy metabolism. The course is taught in approximately four blocks, with review sessions and examinations following each block. Exams are designed to determine mastery of the subject matter and to evaluate the ability to solve problems and logically address research questions. The principles and skills learned through successful completion of the course help prepare students for advanced graduate courses and graduate research careers.