Nucleic Acids Chemistry

Catalog description

Biophysical and biochemical approaches for studying structure-function relationships in nucleic acids. BMMB (CHEM) 572 Nucleic Acids Chemistry (3) The goal of this course is to provide a foundation in biophysical approaches for studying the quantitative and structure-function relationships in nucleic acids systems, including DNA, RNA, and their interactions with proteins, salt, and water. Lectures include basic physical chemistry and statistical mechanics principles along with current literature in the biochemical sciences. At the end of the course, you should be able to meaningfully dissect molecular biological papers at the level of the physical chemistry of these processes. Current topics are introduced through reading and presenting papers from the literature.