Human Anatomy and Development C: Stem Cell Biology and Regenerative Medicine

Catalog description

Exploration of stem cell biology and the role of stem cells in regenerative medicine. ANAT 586 ANAT (PHARM) 586 Human Anatomy and Development C: Stem Cell Biology and Regenerative Medicine (1) This course will provide an evaluation of stem cell biology and regenerative medicine. In particular, discussions will focus on the five sources of embryonic stem cells (adult stem cells, amniotic fluid-derived stem cells, embryonic stem cells derived usingin vitrofertilization technologies, somatic cell nuclear transfer cloning-derived stem cells, and stem cells derived by parthenogenetically-activating oocytes). In addition to providing detailed information on the biology underlying stem cells, group discussions will focus on ethical advantages and disadvantages for each of the five distinct types of stem cells. Work will then turn to current understanding of changes in transcriptome and proteome control of differentiation. As well, discussions will focus on attempts to use stem cells in regenerative medicine. This course will be designed as a mixture of didactic lectures with a particular focus on the current literature. This latter aspect of the course is essential in that much of our current understanding of stem cells has not yet made it into any common text books.