STSC 0343
Why Medical Interventions Work or Fail: A Search for Answers
University of Pennsylvania · UGRD · Fall 2026
Catalog description
The past is littered with interventions that worked or were thought to work that we hold in little regard today – from frontal lobotomies to bone marrow transplants for metastatic breast cancer. Since 1962 the FDA requires proof of efficacy for new drugs. Yet uncertainty surrounds the efficacy and safety of many drugs, technologies, and practices in use today. Will some future observer of today’s practices wonder, as we do about the bleeding and purging of traditional medicine, why we do the things we do? This course will go deep into the social history of modern Western biomedicine to make sense of the ideological, economic, technical, scientific, and social forces shaping the modern medical interventions and the work they do. Students will be introduced to the rewards and challenges of studying medicine as a social and historical process. Case studies of the efficacy of contemporary biomedical interventions will be enriched by in-class meetings with prominent social scientists, biomedical researchers, and clinicians, as well as some potential visits to clinics and historical sites. Each student will develop a research project or essay review related to the efficacy of medical interventions. Most students will likely explore a current or historical controversy over the efficacy and safety of a particular intervention. In addition, there will be two shorter writing assignments.
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