NRSC 0045
A Neuroscience Perspective on Brain Aging
University of Pennsylvania · UGRD · Fall 2026
Catalog description
A recent Netflix documentary, Don’t Die chronicles the life of an individual obsessed with turning back the hands of time- a reflection of our growing cultural and scientific fascination with extending both lifespan and health span. But what is truth and what is myth when evaluating the anti-aging literature? This course will spotlight aging though the lens of neuroscience. We will explore the complexities of brain aging, and in doing so highlight how both lifestyle and genetics can impact the trajectory of neuronal changes with age. Through an inter-disciplinary approach, we will examine societal views of aging, discuss the distinction between ‘normal’ brain aging and neurodegenerative disorders observed in older individuals, and consider how societies can impact the trajectory of an aging population by addressing existing inequities. Through interactive, small group discussions, readings, and guest lectures, students will build on their knowledge of foundational concepts in neuroscience and develop skills in reading and communicating scientific literature. In a world with a rapidly growing population of older individuals, this course will highlight how basic research in neuroscience can inform our lifestyle choices, elder care initiatives and societal approaches to care for an aging society.
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