CHEM 5431
Advanced Organic Chemistry 1
University of Pennsylvania · UGRD · Fall 2026
Catalog description
This course focuses on organic reactions, reaction mechanisms, and the strategic applications of these reactions in organic synthesis. Topics include symmetry, stereochemistry, stereoselectivity, olefinations, olefin metathesis, transition-metal catalyzed cross couplings, cycloadditions, electrocyclizations, sigmatropic rearrangements, and other pericycylic reactions. The material will be illustrated by applications in multistep chemical synthesis. Based on this course, students should be able to read the modern literature, develop independent research proposals in organic chemistry, and succeed in graduate school. Recommended prerequisites: A basic understanding of Lewis structures, molecular orbitals, hybridization, arrow pushing, stability, and reactivity.
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