Bioinformatics, Genomics and Proteomics

Catalog description

This is a second semester course in the MS program of Biochemistry and Molecular Biology. Students will learn the role of epigenetic mechanisms regulating gene expression and the analysis of DNA sequences using OLIGO primer and statistical modelling. In silico detection, multiple sequence alignment and analysis. Instruction on the construction of phylogenetic trees using UPGMA, transformed distance matrix and maximum parsimony methods. The concept of orthologous and paralogous proteins will be introduced and discussed with respect to the role played in protein evolution.