ADVANCES IN MANIPULATING THE HUMAN GENOME

Catalog description

Covers current techniques in genetic engineering used to modify the characteristics of individuals as a prelude to possible future human genetic engineering, including advances in gene manipulation from early recombinant DNA techniques to CRISPR-Cas technology. Emphasizes manipulations of the genomes of individual mammals, and characterization of the effect of those manipulations at levels from the molecular to the physiological. Explores DNA/RNA/protein extraction, polymerase chain reaction, molecular cloning, sequencing (DNA, RNA, and chromatin), expression analyses, gene overexpression, silencing and perturbation.