Principles and Mechanisms of Molecular and Biochemical Toxicology, II

Catalog description

This course covers the biochemical, molecular and cellular mechanisms through which xenobiotics disrupt development and the cardiovascular, immune, nervous, dermal and reproductive systems to produce toxicity and adverse outcomes at the organ/organism level. The course covers emerging contaminants, the role of genetics and epigenetics in individual susceptibility to xenobiotics and the use of "omics' approaches to study the underlying mechanisms of toxicity. Software packages for omics analysis and databases to advance our understanding of mechanisms will be introduced. Principles of epidemiology and community engagement will be discussed and specialized areas of toxicology including regulatory and industrial toxicology and human health risk assessment will be highlighted.