Bioinorganic Chemistry

Catalog description

The interface between inorganic and biological chemistry will be explored, focusing on the catalytic processes in metalloenzymes, and with an emphasis on the diverse roles of transition metals in biology. The physical methods required for the study of bioinorganic systems will be introduced, with application toward determining enzymatic mechanisms. Selected topics will include heme chemistry, nitrogen fixation, C-H bond activation, electron transfer, oxygen transport, metal ion uptake and toxicity, drug activation and/or metabolism by metalloenzymes, and metallodrugs.