Mass Spectrometry and Interpretation of Mass Spectra. 3 credits, 3 contact hours

Catalog description

Prerequisites: CHEM 125 and CHEM 126 or equivalent. Historical background, fundamentals and mechanics of operation for components incorporated into modern Mass Spectrometers: vacuum system, ion sources, mass filter, ion detection, plus computer operation and data collection. Explanation and interpretation of mass spectra and fragmentation patterns are a fundamental theme throughout the course. Lecture material includes principles of operation and appropriate applications for modern types of mass spectrometers: magnetic sector, quadrupole, time of flight, ion trap, FT-ICR. Theory and applications of electron impact, chemical, electrospray, and other ionization techniques including atmospheric sampling are covered. High resolution analysis using magnetic sector and FT - ion cyclotron instruments. Analytical applications in environmental, petroleum and biochemical analysis and applications and coupling of mass spectrometry with other instruments (GC, LC, AES,) are illustrated.