Structural and Functional Genomics

Catalog description

The objective of this course is to teach graduate students cutting-edge technologies used in omics with practical training in online databases and analytical tools. Students are expected to learn basic approaches in functional genomics, including forward and reverse genetics, transposon insertion, RNA interference (RNAi), TILLING (Targeted Induced Local Lesion IN Genomes), fine structure genetics (Modifier screens, Enhancer trap, GAL4 mediated over-expression), and current platforms for genome-editing. Laboratory sections will be computer-based, using publicly available online resources. Students will explore archives and sequence assemblies, analyze single molecules, navigate genome browsers, use comparative mapping tools, and work with phenotype/genotype data for genome-wide association studies (GWAS)