Medicinal Chemistry I Credits: 3

Catalog description

This course is the study of medicinally active substances, both natural and synthetic, which describes their chemical properties, their mode of action, their structure-activity relationships and their metabolic rate. Starting with their origin, it is shown how drugs in a series are developed by chemical modification, quantitative structure activity relationships and receptor theory. The chemical properties of a drug are described and explained. The mode of action of the drug is explained on a biochemical basis whenever possible. Once a drug has had its medicinal effect, it is excreted or metabolized. Reasons for excretion or metabolism are explained.