Cardiovascular Physiology

Catalog description

This course is designed to provide the student with an in depth knowledge of specific aspects of cardiovascular physiology with major emphasis on cardiac structure and function. Topics are covered in 1, 3-4 hour session per week and are based on reading assignments from the literature. The following topics have been addressed in previous offerings but the specific topics may vary from year to year: Heart muscle structure and remodeling, myofilament protein structure/function, sarcomere as a therapeutic target, excitation contraction coupling, cardiomyocyte Ca2+ handling, cardiac myocyte energetics, myocyte survival and cell death pathways, cell-to-cell communication, cardiac remodeling, heart failure, myocardial extracellular matrix, effects of exercise training on cardiac function, regulation of coronary blood flow. Credit Hour s : 4 Prerequisites: MPP 7422 or the equivalent (e.g., UM first year medical school curriculum, V_BSCI 8420, or BIO_SC 3700 -with supporting courses)