Advanced Upstream Processing

Catalog description

The primary goal of this course is to provide students with an advanced background in mammalian cell biotechnology. Biology of cultured cells including cell line generation techniques, scale-up and manufacturing capacity, as well as engineering aspects including aeration and stirring for bioreactor designing will be discussed. This course will aim to further the knowledge of different modes of operation of bioreactors and different cell retention techniques. The course will introduce advanced topics including stem cells and CAR-T-cells from the perspective of clinical/manufacturing challenges and process designs.