Signaling Pathways in Physiology

Catalog description

Current concepts of biological signaling transduction and its role in controlling genes expression and protein synthesis involved in exercise adaptation, including resistance and endurance exercise, and disease states, including cardiovascular disease and cancer. This course seeks to fulfill the following objectives: (1) To train students to understand the molecular and cellular signaling mechanisms associated with changes in skeletal and cardiac muscle mass, cardiac function, and endothelial function change in response to exercise and disease. (2) Foster an understanding of the correlation of 'macro-level' concepts like muscle hypertrophy to 'micro-level' concepts such as mTOR signaling with the goal of understanding the role cell signaling plays in mediating chronic adaptation. This course is recommended for pre-med students, pre-physical therapy students, biology and physiology majors, 80 and those interested in a career in health and human services. This course will cover concepts that are of emphasis of the MCAT exam.