Molecular Biophysics

Catalog description

Survey of the biophysical methods most frequently encountered in biochemistry and related disciplines. A summary of concepts and techniques of physical science used in studying the structure and function of biomacromolecules such as proteins and DNA. Applications include classical equilibrium thermodynamics and analytical methods like mass spectrometry and circular dichroism (CD), fluorescence, EPR and nuclear magnetic resonance (NMR) spectroscopy. An emphasis on the underlying principles and techniques used in determining the molecular weight and shape of biopolymers, biochemical mechanisms of action, and observation of conformational changes in macromolecules.