Enzymology

Catalog description

Enzymology is an advanced biochemistry course where students will explore how enzymes are isolated. The course examines detailed enzyme mechanisms. Students will describe the formation of the enzyme-substrate complex and how enzymes bind substrates, the energetics of enzyme catalysis, and formation of the transition state. Students will learn how to analyze steady-state enzyme activity using substrate velocity curves and Michaelis-Menten kinetics. Students will define the competitive, non-competitive, uncompetitive, and irreversible inhibition along with other factors that alter enzyme activity, such as pH, which are important in human diseases as well as the design of pharmaceuticals.