Methods of Evaluation - Drug Action and Toxicity I

Catalog description

A lecture laboratory course, which encompasses the use of physiological and analytical methods, used in determining the site, mechanism of action, and toxicity of drugs and chemicals. The sequence of laboratory experiments involves interdisciplinary approach incorporating the various areas of pharmacology and toxicology. This includes basic techniques used to monitor drug action and toxicity, evaluating drug action on selected disease states. In vitro biochemical methods used to determine pharmacologic and toxicologic actions, teratogenicity and reproductive toxicity. The analytical techniques include spectro- photometry, gas-liquid chromatography, GC-mass spectrometry, high-pressure liquid chromatography, atomic absorption spectrometry, immunoassays, gel electrophoresis, and tissue cell techniques. Offered fall term, even years.