Advanced Medicinal Chemistry II

Catalog description

This course builds upon the concepts discussed in GPSC 523, Advanced Medicinal Chemistry I. Students entering this course are assumed to be knowledgeable in the following areas and are expected to be able to apply these concepts to a variety of situations: receptors as drug targets, concepts of molecular modification, enzymes as drug targets, mechanistic organic chemistry, pharmacology. This course will discuss advanced concepts including: Quantitative Structure-Activity Relationships, prodrugs and drug delivery systems, bioinformatics, combinatorial/Parallel Synthesis, HTS, DNA interacting agents, RNA interacting agents, analog design, molecular modeling, and discussion of recent advances in medicinal chemistry. Offered spring only.