Advanced Topics in Cellular and Molecular Biology

Catalog description

The aim of this course is to provide an in-depth understanding of some of the main concepts and problems in cell and molecular biology. The course will examine a range of areas of modern cell and molecular biology. How nuclear architecture influences gene expression; how transcription is coupled with other cellular processes; how the coding capacity of genomes is increased through alternative splicing and RNA editing; mechanisms of regulation by non-coding RNAs, DNA repair, cell communication, cell signaling and vesicular trafficking in cells. In addition basic concepts in epigenetics and discuss various epigenetic processes such as DNA methylation, chromatin remodeling, gene imprinting, post-translational histone modification, epigenomics, environmental epigenetics and the relationship between epigenetic modification and human health. The sessions will incorporate aspects of experimental research, and introduce research literature. Topics will also be related to relevant diseases. 002058