Principles of Clinical Pharmacology I

Catalog description

This course provides a basis for understanding the scientific principles of rational drug therapy and contemporary drug development, with emphasis on pharmacokinetics, methods for drug analysis, drug metabolism and pharmacogenetics. Topics include the physiologic and pathophysiologic factors involved in drug absorption, distribution, metabolism and elimination, determinants of variability in drug responses, inter- and intra-patient variability in pharmacokinetics/pharmacodynamics, and drug interactions. This course also provides an introduction to common pharmacokinetic and pharmacodynamic modeling approaches. Prerequisites: Basic knowledge of calculus. Credits: 2.