Introduction to Human Genetics

Catalog description

This undergraduate course focuses on fundamental principles of Mendelian inheritance, applied to the genetic characterization of human diseases. The topics covered include patterns of inheritance for Mendelian human traits, mapping and identification of gene variants and mutations in humans. Elements of cancer genetics, as well as some general principles of genetic testing and counseling are discussed. Aims of the course a) to explore fundamental concepts of inheritance (i.e. structure and function of the genetic material, basic Mendelian genetics principles, mitotic and meiotic cell divisions, control of the cell cycle phases) b) to develop a basic knowledge of Mendelian modes of inheritance in humans, Mutation, Variation in humans and genetic testing, Chromosomal basis of human disease, and Cancer genetics.