PHOL 402B
Physiological Basis for Disease
Case Western Reserve University · UGRD · Fall 2026
Catalog description
Physiological Basis for Disease is a graduate-level course designed to provide the fundamental physiology of a select group of organ systems and examples of how the molecular basis of disease affects physiological function of these systems. As such, PHOL402 will prepare students for future study in advanced biomedical sciences. The course is 3 credit hours and will be offered in the both the Fall (402A) and Spring (402B) semesters of each academic year. Course content of PHOL402 builds on knowledge learned in Medical Physiology-- PHOL481 and PHOL482, and is designed to be taken concurrently or in series with Medical Physiology courses. Topics to be covered during the Fall (402A) semester include pathophysiology of cancer, and select diseases of the central nervous system, cardiovascular system, and urinary/renal system. Topics to be covered in the Spring (402B) semester include select diseases of the respiratory, gastrointestinal, and endocrine systems. The format will be a combination of lectures, in class discussions, and take-home problem sets to facilitate student-directed learning. Grading will be based on problem sets (30%) and weekly quizzes (70%). Due to the course format and large class size, this course is intended primarily for master's students. PhD students that desire to take this course must first seek approval from their graduate program directors.
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