PHOL 401C

Human Physiology: A Molecular Understanding of Organ System Function

Case Western Reserve University · UGRD · Fall 2026

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This course is designed to integrate effectively with PHOL 401A and PHOL 401B , bringing the knowledge of the PhD students to the next level of integration and organ function. Structured on a 2 hour lecture per week, the course will cover the main molecular determinant and signaling components (e.g. neurotransmitters, hormones, adipokines, etc.) that regulate the integrated functioning of our main organ systems: respiratory, renal, cardiovascular, gastrointestinal, central and autonomic nervous systems, and integrated metabolism. The main topics relative to these 6 blocks will be covered in class through lectures, leaving ample opportunity for the students to engage in an interactive discussion with the instructor or among themselves throughout the lecture and at the end of it. Upon completion of each organ system, the students will elaborate on an assigned research article as part of their home-assignment. The intent of this 2-page essay is to assess the application of the knowledge provided in-class to the research topic discussed in the paper, and further integrate the student's knowledge of the academic material discussed. The course will conclude with a final mini-essay exam. Prereq or Coreq: PHOL 401A and PHOL 401B .

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