Since You Were Born: Nobel Prize Biomedical Research in the Last 21 Years- Section B

Catalog description

This course is one of four sections that will cover major advances in biomedical research by review of Nobel Prize-winning topics from the past 21 years. Each section will cover 8 Nobel prize topics (1 topic/2 hour session/week for 8 weeks). Students will read critical research papers of the Nobel prize scientist(s) in preparation for guided in-class discussion led by the faculty mentor. The IBMS 456B section will cover Nobel Prizes related to the areas of Molecular Biology & Microbiology, Molecular Virology, Pathology-Immunology, and Cell Biology. These include: 1) 2016 Prize, Y. Ohsumi: Mechanisms of Autophagy; 2) 2015 Prize, W. Campbell, S. Omura, and Y. Tu: Therapies against roundworms & malaria; 3) 2011 Prize, B. Beutler, J. Hoffman, and R. Steinman: Mechanisms underlying innate immunity and adaptive immunity; 4) 2008 Prize, H. zur Hausen, F. Barre-Sinoussi, and L. Montagnier: Discovery of human immunodeficiency virus and oncogenic papilloma viruses; 5) 2008 Prize, O. Shimomura, M. Chalfie, and R. Tsien: Discovery/development of green fluorescent protein for biological applications; 6) 2005 Prize, B. Marshall and J. Warren: Discovery of Helicobacter pyloris as pathogenic mechanism in peptic ulcers/gastritis; 7) 1999 Prize, G. Blobel: Mechanisms of protein sorting and subcellular trafficking; 8) 1996 Prize, P. Doherty and R. Zinkernagel: Mechanisms of cell-mediated immune defense.