Molecular Endocrinology

Catalog description

A detailed biochemical examination of the hormonal signaling system of the human body and associated diseases. This includes mechanisms of glandular sensing and secretion, including metabolic signaling pathways (insulin and glucagon; leptin and ghrelin), the thyroid and thyroidisms, hypothalamus and pituitary gland, vitamin D and calcium homeostasis, among others. Molecular-level analysis of extra- and intra-cellular signaling pathways will be covered and critical differences in canonical pathways in specific tissue types will be emphasized. Additional topics will include amine neurotransmitters and affective disorders, steroid hormones and nuclear receptors, and circadian rhythm and sleep. Offered as BIOC 344 and BIOC 444 . Prereq: Graduate student standing.