Single Molecule Spectroscopy

Catalog description

Introduces the development and application of single molecule (SM) detection to problems in biology and biochemistry. Topics covered include early pioneers of the field; the principles of instrument design; methods/approaches for sample preparation and probe attachment; single molecule fluorescence spectroscopy/microscopy; super-resolution imaging techniques; force spectroscopy/microscopy; hardware/software considerations for data acquisition and analysis; and a literature survey of current research applications. Prerequisite(s): CHEM 341 or CHEM 351 , and CHEM 401 with a minimum grade of C (2.0); or classified graduate standing.